Liquid Chromatography: Fundamentals and Instrumentation

الغلاف الأمامي
Salvatore Fanali, Paul R. Haddad, Colin Poole, Marja-Liisa Riekkola
Elsevier, 22‏/06‏/2017 - 808 من الصفحات

Liquid Chromatography: Fundamentals and Instrumentation, Second Edition, is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their understanding of new fundamentals and instrumentation techniques in the field.

In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more.

This second edition addresses these new developments with updated chapters from the most expert researchers in the field.

  • Emphasizes the integration of chromatographic methods and sample preparation
  • Explains how liquid chromatography is used in different industrial sectors
  • Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical)
  • Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making
 

المحتوى

Milestones in the development of liquid chromatography
1
Kinetic theories of liquid chromatography
17
Column technology in liquid chromatography
39
Reversedphase liquid chromatography
91
Secondary chemical equilibria in reversedphase liquid chromatography
125
Hydrophilic interaction liquid chromatography
147
Hydrophobic interaction chromatography
171
Liquidsolid chromatography
191
General instrumentation in HPLC
417
Advanced spectroscopic detectors for identification and quantification Mass spectrometry
431
Advanced IR and Raman detectors for identification and quantification
463
Advanced spectroscopic detectors for identification and quantification Nuclear magnetic resonance
479
Data analysis
515
Validation of liquid chromatographic methods
533
Quantitative structure property retention relationships in liquid chromatography
553
Modeling of preparative liquid chromatography
573

Ion chromatography
205
Sizeexclusion chromatography
245
Interaction polymer chromatography
275
Affinity chromatography
319
Solvent selection in liquid chromatography
343
Method development in liquid chromatography
375
Theory and practice of gradient elution liquid chromatography
389
Comprehensive twodimensional liquid chromatography
403
Process concepts in preparative chromatography
593
Miniaturization and microfluidics
619
Nanoliquid chromatography
637
Capillary electrochromatography
697
Ultrahigh performance liquid chromatography
719
Index
771
Back Cover
785
حقوق النشر

طبعات أخرى - عرض جميع المقتطفات

عبارات ومصطلحات مألوفة

نبذة عن المؤلف (2017)

Salvatore Fanali is Director of Research at the Institute of Chemical Methodologies, Italian National Research Council (C.N.R.) in Monterotondo (Rome), Italy, and head of the Capillary Electromigration and Chromatographic Methods Unit at the same Institute. His research activity is mainly focused on separation science including the development of modern miniaturized techniques (electrodriven and liquid chromatography). He also studies hyphenation with mass spectrometry and development of new stationary phases. Separation methods developed are currently applied to food, pharmaceuticals, chiral environment, and biomedical analysis. He is Editor of the Journal of Chromatography A and a member of the advisory editorial board of seven international scientific journals. Fanali is the author of about 300 publications including some book chapters. He received several awards including the “Liberti Medal in Separation Science from the Italian Chemical Society.

Paul Haddad is currently a Distinguished Professor of Chemistry and Australian Research Council Federation Fellow at the University of Tasmania, as well as Director of the Pfizer Analytical Research Centre. He has more than 500 publications in this field and has presented in excess of 450 papers at local and international scientific meetings. He is an editor of Journal of Chromatography A, a contributing editor for Trends in Analytical Chemistry, and was an editor of Analytica Chimica Acta for 6 years. He is currently a member of the editorial boards of 10 other journals of analytical chemistry or separation science. He is the recipient of several national and international awards, including the ACS Award in Chromatography, the Marcel Golay Award, the AJP Martin Gold Medal awarded by the Chromatographic Society, the Royal Society of Chemistry Analytical Separation Methods Award, the RACI HG Smith and Analytical Division medals, and more.

Professor Colin Poole is internationally known in the field of thin-layer chromatography and is an editor of the Journal of Chromatography and former editor of the Journal of Planar Chromatography – Modern TLC. He has authored several books on chromatography, recent examples being The Essence of Chromatography published by Elsevier (2003), and Gas Chromatography published by Elsevier (2012). He is the author of approximately 400 research articles, many of which deal with thin-layer chromatography, and is co-chair of the biennial “International Symposium on High-Performance Thin-Layer Chromatography.

Marja-Liisa Riekkola is a professor of Analytical Chemistry at Helsinki University, Helsinki, Finland. She is well recognized in the field of separation science. She serves as Editor of Journal of Chromatography A. Prof. Riekkola is one of the leaders in chromatography with a large number of publications.

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